Immune system’s role in infections
The COVID-19 project uses a combination of multi-omics approach such as CyTOF, scRNA-seq and flow cytometry to decipher dysregulations in immune compartments specifically emerging in severe disease progression.
The Influenza A virus project uses a combination of scRNA-seq data and flow cytometry to elucidate the effect of TCAIM on memory T cell generation.
Contribution to “non-antigen”-driven diseases
The T2D project uses scRNA-seq as well as spatial multiplex data gathered by IMC to decipher changes in immune cell compartments as a result of high fat/sucrose diet.
Mitochondria - a central hub controlling immune cell activation
The TCAIM project uses FACS, CyTOF, RNASeq, transmission electron microscopy and metabolic GC-MS analysis to investigate the mechanism how TCAIM controls mitochondrial functions to regulate immune cell metabolism and thereby T cell activation and effector functions.
The bone regeneration project aims to determine the key signaling pathways regulated by mitochondria which control immune function and intercellular communication during bone fracture healing by utilizing flow cytometry, scRNASeq, multiplex imaging and metabolic profiling.
Imunoregulatory cell therapy
(coming soon)
T cell differentiation mediated by co-receptors
(coming soon)