COVID-19 & Influenza A
Infectious diseases represent an ample opportunity for basic and translational immunological research. They provide insight into one of the most acute contexts in which the immune system can show its response potential, but also play a pathological role. Elucidating both protective and pathogenic mechanisms behind the disease presentation in COVID-19 and Influenza allows us to lay ground for and attempt modulation of the immune response to reduce the burden of a virus. Additionally, age-specific immune regulation is central to one of our projects and will help to address the growing problem of adapting treatment options for use in a younger population.
- Lev Petrov (CyTOF data analysis)
- Julia Stein (cell culture, FACS, scRNAseq, histology, IMC)
- Tomislav Kostevc (Cell biology)
- Dr. Matthias Barone (IMC data analysis, bioinformatics)
- Katrin Vogt (Cell biology)
- Christine Appelt (MACS, cell culture, flow cytometry)
- Complement activation induces excessive T cell cytotoxicity in severe COVID-19 [Cell 2022, 185(3)]
- Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment [Cell 2020, 182(6)]
- Deciphering the Role of Humoral and Cellular Immune Responses in Different COVID-19 Vaccines-A Comparison of Vaccine Candidate Genes in Roborovski Dwarf Hamsters [Viruses 2021, 13(11)]